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对于阶段1-3慢性肾脏病的饮食危险因素的管理

时间:2016-04-20 13:52:08来源: 作者:www.liuxuelw.com 点击:0
身体健康的人理所当然地认为食品其烹饪,而不是它的生化值。
 
Polyunsaturated fatty acids (PUFA’s) like eicosapentaenoic acid (EPA) exert a beneficial effect on the progression of chronic renal disease in several animal models26,27, both in immune complex glomerulonephritis and in various remnant kidney models28. In a study29, fifteen patients (7 males and 8 females) withdifferent chronic diseases were observed. In period 1 (first 4 weeks), patients were on a low protein diet (30-40g/day, LP). Period 2 is 4 weeks of high protein diet (80-90g/day, HP). Period 3 is 8 weeks of dietary supplementation with 6 capsules super EPA (3g omega-3 fatty acids, HP+EPA). 
Table 2. Median GFR and ERPF at the End of Each Study Period
Period 1 (LP) Period 2 (HP) Period 3 (HP+EPA)
GFR
(ml/min/1.73m2) 33 47 53
ERPF
(ml/min/1.73m2) 140 163 206
GFR: glomerular filtration rate
ERPF: effective renal plasma flow
The result shows that EPA diet increases the GFR and ERPF dramatically. This study proved that administration of omega-3 PUFA’s lead to an increase in renal function in 15 patients with a chronic renal diseae. 
 
In conclusion, nutritional management like limiting protein and phosphorus intake or increase probable vitamin K and PUFA intake will contribute to reduction in the progression of early stages (stage1-3) chronic kidney disease or even advanced kidney disease. 
 
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Reference文献
 
Manley, H.J., 2007. Disease Progression and the application of evidence-based treatment guidelines diagnose it early: a case for screening and appropriate management. Journal of Managed Care Pharmacy, 13(9 Suppl D), S6-12.
Meguid E. N., Adeera L, 2009. Unique aspect of chronic kidney disease in the developing countries. Chronic Kidney Disease. P179.
Klahr S., 1983, Role of dietary factors in the progression of chronic renal disease. Kidney International. Vol. 24, pp579-587
Kristin M. M., Sarah L. B., Xueyan F., Navid S., Judith J. P., Michael A. A., Rachel M. H.,Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease. Kidney International(2013) 83, 835-844.
Klahr S, Schreiner G, Ichikawa I. The progression of renal disease. N Engi Y Med 1988;318:1657-66.
BrennerBM.Nephronadaptationtorenalinjuryorablation.AmJPhysiol1985;249:F324-37.
Joel D. K., History of dietary protein therapy for the treatment of chronic renal disease from the mid 1800s until the 1950s. American Journal of Nephrology 2002. 22:278-283.
Andrew S. L.,Tom G. etc. Dietary protein restriction and the progression of chronic renal disease: what have all of the results of the MDRD study shown? 1999. J Am Soc Nephrol 10: 2426-2439.
Modification of Diet in Renal Disease Study Group (prepared by Levey AS, Adler S, Caggiula AW, England BK, Greene T, Hunsicker LG, Kusek JW, Rogers NL, Teschan PE): Effects of dietary protein restriction on the progression of moderate renal disease in the Modification of Diet on Renal Disease Study. 1996, J Am Soc Nephrol 7: 2616-2626
Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, Striker G, for the Modification of Diet in Renal Disease Study Group: The effects of dietary protein redtriction and blood pressure control on the progression of chronic renal disease. N ENGL Med 330: 877-884, 1994.
United States Department of Agriculture: Nationwide Food Con- sumption Survey 1977–78. Food intakes: Individuals in 48 States, 1977–1978, Report No. I-1, Hyattsville, MD, Consumer Nutrition Division, Human Nutrition Information Service, U.S. Department of Agriculture, 1983, p 439
United States Department of Agriculture: Nationwide Food Con- sumption Survey 1977–78. Food and Nutrient Intakes in 1 Day in the United States, Spring 1977, Report No. I-2, Hyattsville, MD, Consumer Nutrition Division, Department of Agriculture, Sci- ence and Education Administration, 1980, p 15
Food and Nutrition Board, National Research Council: Recom- mended Daily Allowances, 10th Ed., Washington, D.C., National Academy Press, 1989
Kopple JA, Coburn JW: Metabolic studies of low protein diet uremia. I. Nitrogen and potassium. Medicine (Baltimore) 52: 583–595, 1973